Evolvo-Ray

The Evolvo-Ray is a machine built by Dr. Neo Cortex and Dr. Nitrus Brio to evolve ordinary animals into super-sapient beings. Because the Wumpa Islands are located off the coast of Australia, most of its subjects are animals native to that region.

Crash Bandicoot
The Evolvo-Ray first appeared in Crash Bandicoot. It was built by N. Brio, although Cortex claims credit for it. It was used to mutate Ripper Roo, Koala Kong, Pinstripe Potoroo, Komodo Joe & Moe, Tiny Tiger, Tawna Bandicoot, and Crash Bandicoot.

Crash Bandicoot 2: Cortex Strikes Back
The Evolvo-Ray is not seen, but mentioned once by Cortex, who admits that N. Brio invented it. Coco Bandicoot is a possible new subject from it.

Crash Bandicoot: Warped
It is neither seen nor heard of, but there are two possible new subjects in this game: Dingodile and Fake Crash.

Crash Team Racing
Isabella, Megumi, Liz, and Ami are all evolved bandicoots. Possibly subjects of the Evolvo-Ray.

Crash Bash
Cortex is seen in his lab near the Evolvo-Ray in the opening cutscene. N. Ballism's arena also strongly resembles the room the device is found in, and is possibly set somewhere nearby. Only one sure major evolution happened in this game, Rilla Roo. There is some debate as to whether or not the Bearminator was also a subject.

Crash Bandicoot: The Wrath of Cortex
Crunch is the only possible subject from this game. He may have been created through other means, however, as he looks and acts different from the other evolved bandicoots, and is much stronger.

Crash Twinsanity
The Evolvo-Ray did not appear again until Crash Twinsanity, though only as a prototype version in the past. Cortex had been trying to make it as a child (before Brio successfully made it). Cortex's two test subjects were his parrots: Victor and Moritz. However, instead of evolving them, it sent them to the Tenth Dimension. Nevertheless, Cortex quickly got over the loss of his parrots (the only creatures he didn't "loathe or eat") and continued his studies. A newer version of the prototype Evolvo-Ray appeared at the end of the game, infused with the Psychetron, where Cortex tried to dispose of Crash the same way he did with Victor and Moritz. However, the machine malfunctions and sends Cortex into Crash's brain. Also, the hated chef Rusty Walrus may have been an experiment.

Crash of the Titans
The new, mojo-fueled Evolvo-Ray had a major appearance in this game. It was used to give Uka Uka a body which was later destroyed by Crash. The handheld ray gun version of the Evolvo-Ray,  powered by mojo, was able to mutate the animals of Wumpa Island into ferocious titans and make them obey Cortex, N. Gin, Nina, Tiny, and Uka Uka. The game's intro cutscene also depicts Crash's creation with a handheld gun that presumably represents the Evolvo-Ray.

Crash: Mind Over Mutant
The Evolvo-Ray was mentioned by Doctor Nitrus Brio, who claimed to be the true inventor of the device and other inventions used by Cortex. However, it made no physical appearance in the game.

Crash Bandicoot 4: It's About Time
Fake Coco is an evolved bandicoot introduced in It's About Time and likely a subject of the Evolvo-Ray.

Gallery
Evolvo-Strahl Rayon-Evolvo Evolvo-Ray Evolvo-Ray Evolvo-Ray Эволво-Рэй