N. Brio (Boss Fights)

Dr. Nitrus Brio is a boss in Crash Bandicoot and Crash Twinsanity (where he is fought alongside Dr. Nefarious Tropy). He appears in Crash: Mind over Mutant, but within Crunch's boss fight.

Crash Bandicoot
After getting past Lab Assistants, through dark hallways and many machinery Crash is now facing the fifth boss of the game and the second boss of the third island, Dr. Nitrus Brio. He also has the biggest number of hit points as he has nine, however, they go down quickly. At the start Brio is mixing green and red liquids together. Crash arrives near him and Brio raises his potions, smashing them together to cause an explosion. After a quick mix Brio will throw a green potion. When it smashes a green blob will emerge. Crash needs to jump on it as spinning it would just send it across the room. Once Crash does, one of Brio's hit points will go down.

Next, Brio throws a red potion which just explodes once it hits the ground. Then, he throws two more green potions. Once Crash jumps on them Brio will have six hit points. He'll then throw three red potions and three green potions. After Crash gets rid of the blobs, Brio will be left with three hit points.

Brio will then throw six red potions. This time he doesn't throw any green potions, instead choosing to a red potion. His face turns green and then he turns into a monster. He then starts pounding the floor, causing rubble to fall from above, and heads for Crash. Crash can jump on the pieces and jump onto Brio's head. Once this is done three times, Brio is defeated.

Crash Twinsanity
In Twinsanity, N. Brio acts as a mini-boss, the real boss being N. Tropy. The doctor will drink a green liquid and jump in the water. When he comes back, he transforms himself in a big monster. He has no hit points and can't be hit; Crash just needs to avoid him, since he'll start jumping around chasing the Bandicoot.

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Crash: Mind Over Mutant
N. Brio briefly appears at the end of the Crunch boss fight. Once Crunch has been defeated and jacked, Crash must use him to fire at N. Brio who is running back and forth in the background area. Once hit, he is knocked down into the flames and the fight is over.

Trivia

 * N. Brio was originally supposed to fight Crash alone in Crash Twinsanity.
 * N. Brio had the most health in Crash Bandicoot.